Ozara
Sanctum Ophidia
A lamia in the Serpent's service, and the third boss of Sanctum Ophidia.
Popular builds
The builds groups run most often at this boss, one per role. Ranked by how often each is run, not by damage done.
Most popular Tank build
DragonKnight tank with Pearlescent Ward and Tremorscale
seen 4×
Skills
Turning Tide7 
Pearlescent Ward5 
Tremorscale2 Most popular Healer build
Warden healer with Symphony of Blades
seen 4×
Skills
Spell Power Cure5 Pillager's Profit5 
Symphony of Blades2 
Grand Rejuvenation2 Most popular DPS build
Arcanist DPS
seen 49×
Skills
Spattering Disjunction5 
Perfected Slivers of the Null Arca5 
Merciless Charge2 
Slimecraw1 
Velothi Ur-Mage's Amulet1 Most popular Support build
Nightblade Werewolf
seen 18×
Skills
Savage Werewolf5 Perfected Slivers of the Null Arca5 Perfected Merciless Charge2 
Valkyn Skoria1
Ranked by how often a build is run, from the top 100 boss-DPS parses per boss. U50 data, as of 4 Aug 2026.